Mid-term impact of patient-prosthesis mismatch on young and middle-aged patients undergoing surgery due to severe aortic stenosis

Methods All patients younger than 70 years of age undergoing isolated aortic valve replacement from October 2005 to October 2011 were analyzed. Patient-prosthesis mismatch was defined as the indexed effective orifice area ≤ 0,85cm2/m2. We studied the impact of patient-prosthesis mismatch on mid-term overall mortality, cardiac events and New York Heart Association functional class using an analysis stratified for propensity score. Cardiac events were defined as cardiac death, sudden death, hospital readmission due to angina, syncope or heart failure or reoperation on aortic prosthesis.